Didn't totally understand your question... But, the analog outs off course are better because they are the sound that comes direct from your Virus. And they are free of latency. But you cannot get the sounds inside your sequencer... The USB mode uses a A/D (Analog to Digital) conversion and this cause a loss of the quality. But like synthfiend the A/D's on the Virus are pretty good!
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Virus Snow, JP-8000, Juno-G, Macbook Pro, Logic 9, HS-80, NRV-10.
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