Historically I agree with regarding PCI(e) for interfaces/bandwidth however i finally stretched myself to a RME FF800 and do not regret it.
Very clear sound, excllent configuration (especially it using input/outputs for external buses/effects/synths/outboard gear in general).
The nice thing with firewire is being forunate enough to have a macbook pro i can play around with samplers/reason/cubase on the move and hook it up FF800 between the lappy and desktop pc so suits me.
I read loads about audio interfaces and tbh the RMEs are highly spoken of on every forum i visited. Went to the local store to hear it vs motu and echo audio, rme won hands down for me. Loving it ...
Links :
http://www.tweakheadz.com/soundcards...interfaces.htm
http://www.gearslutz.com/board/music...ml#post3839726
d•.•p