I attended a dnb lecture from Shockone the other day - he uses only audio samples in Cubase 5 to write his drum tracks and not midi/step. Hearing the results you can hear why - I normally would use a drum sampler/vst like Battery or Groove Agent but I am trying the older method with audio samples and I think it sounds a lot fatter.
Note this doesnt mean breaks or loops - you would use individual kick drums, snares, hats, + overlapping breaks etc - and control it all by grouping.
Being able to control clip volumes you can still program quite intuitively and dynamically.
That said - for writing its easier to fire in a quick midi pattern instead of dragging clips into place.
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