I did install the newest OS, I had even
more problems than before so I rolled back. I don't use a hub and I usually try not to have anything else connected to USB at all.
What kind of computer are you on? I'm on a Quad core i7 Macbook Pro. It seems to run more consistently on my desktop (late 2009 Mac Pro) but I still do have some sync problems at some point during every session.
I have some money saved so I will probably just bite the bullet and buy a used TI2 desktop soon ...