Do you own the Virus ti? I think you can probably benefit from the feedback character thing.
You need a very noisy source: you can set the oscillators apart by octaves (12 semitones either way). At this point, you can go a number of different ways, keeping in mind you want a very noisy and full source. Try to turn the sync on and off to see if you like the timbre. When doing that, turn the FM amount knob (with sync on and off). It should be set to "pos tri" as default, but try out the other modes: noise can be cool for what you're looking for, also wave - in which case oscillator's one wave, that's with shape knob turned all the way left and choosing one wave to modulate. Classic sound is with sine waves, but there's nothing preventing you from using the others of course...
You can also try Pulse Width Modulation: for a very frenetic sound, modulate the OSC shape with a fast LFO.
We're still on the Oscillator's section and there's plenty of ways to go for very busy sources. I didn't mention Wavetables or Hypersaw, because I own the C - but I bet those are good for getting very busy sound sources as well. Wavetables can work pretty much like you'd set up a frenetic PWM sound, fast lfo scanning the wavetable.
You can also add noise to taste for even more busy and dirty sound source.
The rest of it is about the filters: analogue filter will provide you with self oscillating byte, but you won't be able to choose the saturation mode, it's just analogue boost and that's it! Try turning that up and push the resonance way up there. The resonance is key to this kind of sounds - all of them that you're constantly asking for. And filter envelope modulation is also the way to go imo. So, this is just a random example. Turn the filter envelope's polarity to negative . Place your Cutt off Knob almost entirely to the right. Then all values to 0 and only some decay. Make sure you're only earing one filter at this stage, so filter balance all the way left. Ok, by playing with filter envelope you can adjust the sweep on the frequencies. Make sure you set the amount right to, you're looking for a sweep from high frequencies to low mids at most - not all the way into the low end.
Another filter is taking a nap right now, so why not use a high pass filter to get rid of the muddy lows? Or the good old BS to get a more nasal tone (used a lot in DNB)...
Add distortion into the mix: try rectifier for starters, make sure there's plenty going!
Does it scream or not? You'll want to focus on getting the busy source and fine tunning the filter stage with very short tweaks at a time. Even after you've placed the fx there, you need to go back to filter stage. You're basicly exciting the distortion with tons of resonance and a very busy and noisy source. The PAOU or UAIIII sounds are nothing more then filter sweeps. Not that I wouldn't try to use the frequency shifter if I were you. But this is the basics and those sounds you're looking for can be done - almost no exception - with even analogue synthesizers as there's no mad modulation going.
Despite all this: please, by all means, just get yourself a nice distortion plug-in, multi-band is better, and make it your personal diet to learn it throughly - search youtube! It's not that hard and you'll be the king of synth screams in no time! Even if I'd sent you a complete sound packed with the processing chain, you'd still have to mix it in your tunes, right? So go for it dude!!
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