Try connecting by using S/PDIF which will give you the same digital quality you're getting with USB, but maybe with better reliability (if you have issues with USB audio)
I don't think it's good idea to connect the Virus with TRS because you're introducing D/A conversion from Virus to analog outputs and then the interface is performing another A/D conversion to get the audio inside. By using S/PDIF, there's no need to perform those conversions
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