I don't know how about mac, but on win system you can usually use just one soundcard at time, however when using daw most likely you will be able to configure it to use both at same time so you can redirect the signal from virus to nrv, but perhaps with doubled latency. If I remember correctly in ableton it was possible to set NRV10 as its audio interface and receive sound from virus from vst plugin via usb, but I can also be mistaken. Anyway, I think, running several audio systems on PC you cannot expect 100% stable system - problems may appear anyway.
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